XELEVIA 50MG TABLET (TABLET)
Contents
Sitagliptin phosphate
Indications / Uses
Adjunct to diet & exercise to improve glycemic control in patients w/ type 2 DM. In combination w/ PPAR-γ agonist (eg, thiazolidinediones) or metformin as initial therapy or when the single agent alone, w/ diet & exercise do not improve adequate glycemic control. Combination therapy w/ a sulfonylurea in patients w/ type 2 DM to improve glycemic control when treatment w/ single agent alone, w/ diet & exercise do not provide adequate glycemic control. In combination w/ metformin & sulfonylurea, metformin & PPAR-γ agonists (eg thiazolidinediones) when dual therapy w/ these agents does not provide adequate glycemic control. Adjunct to diet & exercise to improve glycemic control in combination w/ insulin (w/ or w/o metformin).
₱55.81
Availability:
In stock
SKU
13984
Dosage / Direction for Use
Monotherapy or combination therapy w/ metformin, sulfonylurea, insulin (w/ or w/o metformin), PPAR-γ agonist, metformin + sulfonylurea or metformin + PPAR-γ agonist 100 mg once daily.
Administration
May be taken with or without food.
Contraindications
Type 1 DM, diabetic ketoacidosis.
Special Precautions
Patients w/ renal insufficiency (including moderate & severe renal insufficiency), ESRD requiring hemodialysis or peritoneal dialysis. Assess renal function. Lower dose of sulfonylurea or insulin to reduce the risk of hypoglycemia. Hypersensitivity reactions. Inform patients on the symptomatic characteristic of acute pancreatitis. Pregnancy & lactation. Elderly. Childn <18 yr.
Side Effects / Adverse Reactions
Hypoglycemia; abdominal pain, nausea, vomiting, diarrhea, dyspepsia, flatulence; hypersensitivity reactions; exfoliative skin conditions including Stevens-Johnson syndrome; influenza, headache, cutaneous vasculitis, acute pancreatitis, worsening renal function. Resp tract infection, nasopharyngitis, constipation.
Interactions
Digoxin & cyclosporine.
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