Dosage / Direction for Use
Zoltax Adult Uncomplicated UTI 125 mg bid. Resp tract infections 250-500 mg bid. Pneumonia or acute exacerbations of chronic bronchitis 1.5 g bid or 750-mg parenteral dose bid followed by 500-mg tab bid. Lyme disease 500 mg bid for 20 days. Uncomplicated gonorrhea Single 1-g oral dose & 1 g probenecid. Zoltax Injection Usual dose: 750 mg to 1.5 g 8 hrly for 5-10 days. Uncomplicated UTI & pneumonia, skin & skin structure infection, disseminated gonococcal infection 750 mg 8 hrly. Severe or complicated infections, bone & joint infections 1.5 g 8 hrly. Bacterial meningitis Dose should not be >3 g 8 hrly. Pre-op prophylaxis 1.5 g dose IV before surgery or at anesth induction (then 12 hrly for a total of 6 g).
Administration
Should be taken with food.
Contraindications
Hypersensitivity to cephalosporins.
Special Precautions
Renal impairment.
Side Effects / Adverse Reactions
Diarrhea, nausea, vomiting, erythema multiforme, Stevens-Johnson syndrome, toxic epidermal necrolysis.
Interactions
Probenecid, oral estrogen/progesterone contraceptives.