ZITHROMAX 500MG TABLET 3S (PACK)
Contents
Azithromycin dihydrate
Indications / Uses
Infections caused by susceptible organisms in upper resp (including sinusitis & pharyngitis/tonsilitis) & lower resp (including bronchitis & pneumonia) tract, skin & soft tissue infections, acute otitis media. Uncomplicated genital infections due to Chlamydia trachomatis, chancroid due to Haemophilus ducreyi & uncomplicated genital infection due to non-multiresistant Neisseria gonorrhoea; concurrent infection w/ Treponema pallidum should be excluded. Alone or in combination w/ rifabutin for prophylaxis against Mycobacterium avium intracellulare complex (MAC) infection. In combination w/ ethambutol for the treatment of disseminated MAC (DMAC) infection in patients w/ advanced HIV infection. Inj: Community acquired pneumonia (CAP) caused by Legionella pneumophila & pelvic inflammatory diseases (PID) caused by Chlamydia trachomatis, Neisseria gonorrhoea, Mycoplasma hominis) in patients who require initial IV therapy.
₱487.69
Availability:
In stock
SKU
14187
Dosage / Direction for Use
Tab/Susp Adult Treatment of STD caused by Chlamydia trachomatis, Haemophilus ducreyi 1,000 mg as a single dose. Susceptible Neisseria gonorrhoeae 1000 or 2000 mg in combination w/ cerftriaxone 250 or 500 mg. Prophylaxis against MAC infection in patients w/ HIV 1,200 mg orally once/wk. DMAC infection in patients w/ advanced HIV 600 mg once daily. Susp Strep pharyngitis 3-day regimen: Childn >45 kg Adult dose, 36-45 kg 400 mg once daily on days 1-3, 26-35 kg 300 mg once daily on days 1-3, 15-25 kg 200 mg once daily on days 1-3, <15 kg 10 mg/kg once daily on days 1-3. 5-day regimen: Childn >45 kg Adult dose, 36-45 kg 400 mg on day 1, then 200 mg once daily on days 2-5, 26-35 kg 300 mg on day 1, then 150 mg once daily on days 2-5, 15-25 kg 200 mg on day 1, then 100 mg once daily on days 2-5, <15 kg 10 mg/kg on day 1, then 5 mg/kg once daily on days 2-5. Inj Adult CAP 500 mg as a single dose by IV infusion for at least 2 days. PID 500 mg as a single dose by IV infusion for 1-2 days. All indications Adult 500 mg/day for 3 days or alternatively, given for 5 days w/ 500 mg on day 1, then 250 mg on days 2-5. Childn Total dose: 30 mg/kg. Max: 1,500 mg. Do not administer as IV bolus or IM inj.
Administration
May be taken with or without food: May be taken w/ meals to reduce GI discomfort.
Contraindications
Hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic.
Special Precautions
Hypersensitivity. Hepatoxicity. Infantile hypertrophic pyloric stenosis. Ergotism. Superinfection. Clostridium difficile-associated diarrhea. Renal impairment. QT interval prolongation. Fructose intolerance, glucose-galactose malabsorption or saccharase-isomaltase deficiency. Myasthenia gravis. Pregnancy & lactation.
Side Effects / Adverse Reactions
Transient episodes of mild neutropenia; hearing impairment; nausea, vomiting, diarrhea, loose stools, abdominal discomfort (pain/cramps) & flatulence; abnormal liver function; allergic reactions including rash & angioedema; local pain & inflammation at the site of infusion.
Interactions
Reduced peak serum conc w/ antacids. Increased serum levels of digoxin & colchicine. Possibility of interaction w/ ergot derivatives. Zidovudine. Atorvastatin. Elevated Cmax & AUC w/ cyclosporin. Fluconazole. Rifabutin.
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