Special PrecautionsL:
Care should be taken with patients suffering from thyrotoxicosis. Although no teratogenic effects have been observed in animals or in patients, its use during the first trimester of pregnancy is not recommended.
Adverse Reactions:
The frequency of side effects is low at the recommended doses. Recorded side effects i.e. tremor, muscle cramps and palpitations are all characteristics of sympathomimetic amines. These effects usually disappear within the first week of continuous treatment.
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Dosage / Direction for Use:
Tablet: Usual adult dose is 1 to 2 tablets 3 times a day.
Children aged 12 to 15 years take 1 tablet 3 times a day.
Administered at approximately 6 hours intervals.
In most patients, the optimum single dose is 2 tablets.
In patients unusually sensitive to sympathomimetic amines, initiate treatment with 1 tablet 3 times a day.
If adequate bronchodilation is not obtained, the dose may be increased to 2 tablets.
Syrup: To be taken 3 times a day.
Adult and children over 15 years: 10-15 mL (2-3 tsp).
Children 7-15 years: 5.0-10 mL (1-2 tsp).
Children 3-7 years: 2.5-5.0 mL (½-1 tsp).
Children below 3 years: Not recommended.
(5 mL is equivalent to 1 teaspoonful.)
Nebulizing solution: TERBUTALINE sulfate (PULMOXCEL) Nebulizing Solution 2.5 mg/mL is used with dilution.
A multiple dose unit of 10 mL contains 25 mg Terbutaline sulfate.
Inhale 1 mL of Solution containing 2.5 mg Terbutaline sulfate every 6 hours (or 4 times in 24-hour period).
If the entire dose is not inhaled at once occasion, the solution is stable for 24 hours in the reservoir of the nebulizer.
NOTE: The patient's inhalation technique should be checked regularly and the optimal dose of terbutaline should be adjusted for each nebulizer. If the effect of the inhalation is reduced, the patient should seek medical care.
Non-selective blocking agents may partly or totally inhibit the effect of beta-stimulants.