PROLIX SYRUP 10MG 60ML (BOTTLE)

Dosage / Direction for Use 5-60 mg daily in divided doses or as a single daily morning dose or as a double dose on alternate days. Tab Immunosuppressive 10-100 mg daily. Primary & secondary adrenocortical insufficiency 5-25 mg daily in divided doses. Adrenogenital syndromes 10-20 mg/m2 daily in divided doses. Administration Should be taken with food. Contraindications Systemic fungal infections, glaucoma, gastric & duodenal ulcers, certain viral infections & severe psychoneuroses. Special Precautions Heart disease, HTN, renal dysfunction, peptic ulcer, systemic fungal infection, history of psychotic disorders, diabetes, TB, osteoporosis, glaucoma, myasthenia gravis, diverticulitis, colitis & viral diseases like herpes. Monitor adverse effects eg, hyperglycemia, glucosuria, Na retention w/ edema, HTN, osteoporosis & fungal infection in patients receiving high dose or on long-term therapy. Avoid abrupt discontinuation of treatment. Side Effects / Adverse Reactions Adrenal suppression; GI distress, nausea, peptic ulcer, behavioral disturbances, fluid & electrolyte imbalance, visual disturbances, growth retardation, skin atrophy, moon face, Cushingoid state, hirsutism & muscle atrophy. Interactions Reduced effect w/ anticonvulsants, phenobarb, phenytoin, antihistamines, barbiturates, ephedrine, primidone & rifampicin. May reduce the efficacy of hypoglycemics, diuretics, salicylates & anticholinesterases. Enhanced effect w/ aspirin & estrogen. Cyclosporine.