HARNAL OCAS 400MCG TAB (TABLET)

Dosage / Direction for Use: 1 tab daily, to be taken with or without food. Administration: For oral use. The tablet should be swallowed whole, and should not be crunched or chewed as this will interfere with the prolonged release of tamsulosin. Overdosage: Symptoms: Overdosage with tamsulosin hydrochloride can potentially result in severe hypotensive effects, dizziness and malaise. Severe hypotensive effects have been observed at different levels of overdosing. Treatment: In case of acute hypotension occurring after overdosage, cardiovascular support should be given. Blood pressure can be restored and heart rate brought back to normal by lying the patient down. If this does not help, then volume expanders, and when necessary, vasopressors could be employed. Renal function should be monitored and general supportive measures applied. Dialysis is unlikely to be of help, as tamsulosin is very highly bound to plasma proteins. Measures eg, emesis, can be taken to impede absorption. When large quantities are involved, gastric lavage can be applied, and activated charcoal and an osmotic laxative eg, sodium sulfate can be administered. Contraindications: Hypersensitivity to tamsulosin hydrochloride or to any other component of Harnal OCAS. History of orthostatic hypotension; severe hepatic insufficiency.