Dosage / Overdosage:
Usual Initial Dose: 30 mg once daily, increased if necessary up to maximum of 120 mg daily.
It has a duration of action of 12-24 hrs.
Administration: Gliclazide is given by mouth in the treatment of type 2 diabetes mellitus.
Contraindications: Severe hepatic and renal impairment. Porphyria, sulfonylureas may precipitate an acute post attack. Insulin therapy may be given instead. Sulfonylureas are contraindicated in the presence of ketoacidosis.
Use in pregnancy & lactation: Pregnancy and breastfeeding is contraindicated.