BACTIV TAB 1G (TABLET)

Administration May be taken with or without food: Take at the start of a meal for better absorption & to minimize GI intolerance. Contraindications Penicillin hypersensitivity. Possible cross-sensitivity w/ other β-lactam antibiotics eg, cephalosporins. History of penicillin-associated jaundice/hepatic dysfunction. Special Precautions Hepatic dysfunction, moderate to severe renal impairment. Periodic assessment of hepatic, renal & hematopoietic function during prolonged therapy or in patients w/ severe hepatic impairment. Maintain adequate fluid intake & urinary output especially in high doses of amoxicillin. Avoid prolonged use. Prolonged bleeding & prothrombin time. Concomitant use w/ anticoagulants. Pregnancy & lactation. Side Effects / Adverse Reactions Diarrhea, pseudomembranous colitis, indigestion, vomiting, mucocutaneous candidiasis, nausea, hepatitis, cholestatic jaundice. Moderate & asymptomatic rise in AST, ALT or alkaline phosphatase; urticarial & erythematous skin rashes; transient leukopenia & thrombocytopenia. Inj: Local irritation, induration & phlebitis at inj site. Interactions Decreased renal tubular secretion w/ probenecid. Disulfiram-like reaction w/ alcohol. Reduced efficacy of OCs.