VIRLIX 10ML DROPS (BOTTLE)

Dosage / Direction for Use Adult & childn >12 yr 10 mg (20 drops or 10 mL oral soln or 1 tab) once daily. Starting dose: 5 mg (10 drops or 5 mL oral soln or ½ tab). Childn 6-12 yr 5 mg (10 drops or 5 mL oral soln or ½ tab) bid, 2-6 yr 2.5 mg (5 drops or 2.5 mL oral soln) bid. Mild renal impairment (CrCl 50-79 mL/min) 10 mg once daily. Moderate renal impairment (CrCl 30-49 mL/min) 5 mg once daily. Severe renal impairment (CrCl <30 mL/min) 5 mg once every 2 days. Administration May be taken with or without food: Oral drops: Dilute in liqd. Contraindications Hypersensitivity to cetirizine, hydroxyzine or piperazine derivatives. Severe renal impairment (CrCl <10 mL/min). Special Precautions Concomitant use w/ alcohol. Increased risk of urinary retention. Epileptic patients & those at risk of convulsions. Wash-out period of 3 days before allergy skin test. Decreased rate of absorption w/ food. May impair ability to drive or operate machinery. Pregnancy & lactation. Tab: Rare hereditary problems of galactose intolerance, Lapp lactase deficiency. Childn <6 yr. Tab & soln: Glucose-galactose malabsorption. Soln: Rare hereditary problems of fructose intolerance, sucrase-isomaltase insufficiency. Soln & drops: Allergic reactions may occur due to methyl- & propyl p-hydroxybenzoate. Side Effects / Adverse Reactions Fatigue; dizziness, headache; abdominal pain, dry mouth, nausea, diarrhea; somnolence; pharyngitis, rhinitis. Interactions May cause additional reductions in alertness & impairment of performance w/ alcohol or other CNS depressants.