SORBIFER DURULES (TABLET)

Dosage: Adults and Teenagers: 1 durule daily. Ferrous sulfate provides adequate therapy for the majority of patients. When a more rapid Hb response is required, an extra dose in the morning is of advantage. If necessary, the dosage may be further increased by 1 or 2 tabs daily. Prophylaxis During Pregnancy: During the 1st-6th month of pregnancy, 1 durule daily. During the final months, the dosage should be increased to 1 durule morning and evening. Treatment should be continued for at least 2 months after the normal hemoglobin value for the patients has been achieved. Individual long-term therapy, continuous or intermittent, is often necessary in case of continuing major blood loss. Administration: The durules should be swallowed whole and not to be split or chewed. May be taken with meals to reduce gastrointestinal discomfort. Special Precautions: The patients should be warned that iron products can give rise to poisoning in infants. Mechanism of Action: Antianemic. Sorbifer Durules provide continuous release of active substance. Studies using the double-isotope technique have shown that iron administered in the form of ferrous sulfate durules is better utilized by the body than iron in ordinary tablets. The good absorption does not result in increased side effects. The occurrence of nausea and gastric pain is less with ferrous sulfate durules than with conventional tablets.